Article
Associations and interaction effects of maternal smoking and genetic polymorphisms of cytochrome P450 genes with risk of congenital heart disease in offspring: A case-control study.
Medicine - 11 Jun 2021
Diao Jingyi, Zhao Lijuan, Luo Liu, Li Jinqi, Li Yihuan, Zhang Senmao, Wang Tingting, Chen Letao, Huang Peng, Qin Jiabi
Abstract excerpt
ABSTRACT: To assess associations and interactions of maternal smoking and cytochrome P450 (CYP450) genetic variants with the developments of congenital heart disease (CHD) and specific subtypes.A case-control study of 654 cases and 666 controls was conducted from November 2017 to March 2020. The exposures of interest were maternal active and passive smoking before/in the early pregnancy and CYP450 genetic...
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