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Article

Maternal medication use, fetal 3435 C>T polymorphism of the ABCB1 gene, and risk of isolated septal defects in a Han Chinese population.

Pediatric cardiology - 1 Oct 2014

Wang Chuan, Zhou Kaiyu, Xie Liang, Li Yifei, Zhan Yalan, Qiao Lina, Qin Chaoyi, Liu Ruiqi, Hua Yimin

Abstract excerpt

The fundamental etiology of the majority of nonsyndromic congenital heart defects is commonly believed to involve the interaction of multiple environmental and genetic factors. This study aimed to explore the joint effects of fetal 3435 C>T polymorphism in the ABCB1 gene and maternal medication use on the risk of septal defects in a Han Chinese population. An age- and gender-matched case-control study involving...

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Source

Identifiers

PMID: 24740628
DOI: 10.1007/s00246-014-0906-6

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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