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Assessment of evidence on reported non-genetic risk factors of congenital heart defects: the updated umbrella review

29 Apr 2022

Abstract excerpt

BACKGROUND: Congenital heart defect (CHD) is the leading cause of birth defects globally, which results in a great disease burden. It is still imperative to detect the risk factors of CHD. This umbrella review aimed to comprehensively summarize the evidence and grade the evidence of the associations between non-genetic risk factors and CHD. METHODS: Databases including Medline, Embase, Web of Science, Cochrane...

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PMID: 35488214
DOI: 10.1186/s12884-022-04600-7

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