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[Association of maternal MTHFD1 and MTHFD2 gene polymorphisms with congenital heart disease in offspring].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 15 Jul 2022

Chen Qian, Huang Peng, Song Xin-Li, Liu Yi-Ping, Sun Meng-Ting, Wang Ting-Ting, Zhang Sen-Mao, Qin Jia-Bi

Abstract excerpt

OBJECTIVES: To study the association of maternal methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) and methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) gene polymorphisms with congenital heart disease (CHD) in offspring. METHODS: A hospital-based case-control study was conducted. The mothers of 683 children with CHD alone who attended Hunan Children's Hospital, from November 2017 to March 2020 were enrolled as...

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Identifiers

PMID: 35894196
DOI: 10.7499/j.issn.1008-8830.2203002
PMCID: PMC9336623

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