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Article

Structures of the peptidase-containing ABC transporter PCAT1 under equilibrium and nonequilibrium conditions.

Proceedings of the National Academy of Sciences of the United States of America - 25 Jan 2022

Kieuvongngam Virapat, Chen Jue

Abstract excerpt

ATP-binding cassette (ABC) transporters are ubiquitous molecular pumps that transport a broad range of substrates across biological membranes. Although the structure and function of ABC transporters has been studied extensively, our understanding of their energetics and dynamics remains limited. Here, we present studies of the peptidase-containing ABC transporter 1 (PCAT1), a polypeptide processing and secretion...

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Identifiers

PMID: 35074919
DOI: 10.1073/pnas.2120534119
PMCID: PMC8794836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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