Article
Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II.
Frontiers in immunology - 1 Jan 2021
Hyun You-Seok, Lee Yong-Hun, Jo Hyeong-A, Baek In-Cheol, Kim Sun-Mi, Sohn Hyun-Jung, Kim Tai-Gyu
Abstract excerpt
Common human coronaviruses have been circulating undiagnosed worldwide. These common human coronaviruses share partial sequence homology with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); therefore, T cells specific to human coronaviruses are also cross-reactive with SARS-CoV-2 antigens. Herein, we defined CD4+ T cell responses that were cross-reactive with SARS-CoV-2 antigens in blood collected...
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