Article

HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era

2022-09-14

Abstract excerpt

HLA antigen presentation and T-cell immunity are critical to control viral infection such as SARS-CoV-2. This study performed on samples collected in the pre-COVID-19 era demonstrates that individuals are fully equiped at the genetic level in terms of TCR repertoire and HLA variants to recognize and kill SARS-CoV-2 infected cells. HLA diversity, heterologous immunity and random somatic TCR recombination could expl...

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Literature Corpus work: c892e96f-2769-5962-9f73-e79e843672d9
DOI: 10.1101/2022.09.14.507948

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