Article
rs9390123 and rs9399451 influence the DNA repair capacity of lung cancer by regulating PEX3 and PHACTR2‑AS1 expression instead of PHACTR2.
Oncology reports - 1 Mar 2022
Shi Qiang, Shi Qiao-Na, Xu Jiang-Wei, Wang Hong-Yan, Li Ya-Jie, Zhang Xin-Xin, Fu Yu-Hang, Tian Ru-Hui, Jiang Ru, Liu Chun-Chun, Sun Chang
Abstract excerpt
Lung cancer is a common cancer type, and has the highest mortality rate in the world. A genome‑wide association study suggests that the genetic marker rs9390123 is significantly associated with DNA repair capacity (DRC) in lung cancer. Analysis of the data derived from the 1000 Genomes Project indicated that there is another single nucleotide polymorphism (SNP), rs9399451, in strong linkage disequilibrium with...
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