Article
rs66651343 and rs12909095 confer lung cancer risk by regulating CCNDBP1 expression.
PloS one - 1 Jan 2023
Shi Qiang, Ruan Ji, Yang Yu-Chen, Shi Xiao-Qian, Liu Shao-Dong, Wang Hong-Yan, Zhang Shi-Jiao, Wang Si-Qi, Zhong Li, Sun Chang
Abstract excerpt
Lung cancer is a malignant tumor with high rates of mortality and shows significant hereditary predisposition. Previous genome-wide association studies suggest that rs748404, located at promoter of TGM5 (transglutaminase 5), is associated with lung carcinoma. By analysis of 1000 genomes project data for three representative populations in the world, another five SNPs are identified to be in strong linkage...
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