Article
Genetic polymorphism of APE1 rs1130409 can contribute to the risk of lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Jin Feng, Qian Chengyuan, Qing Yi, Zhang Zhimin, Wang Ge, Shan Jinlu, Dai Nan, Li Zheng, Wang Dong
Abstract excerpt
Accumulative evidence suggests that polymorphism in the APE1 gene may have association with the etiology of lung cancer by modulating DNA repair capacity. Many studies have evaluated the association with great discrepancies in the results. The present meta-analysis was undertaken to clarify the effects of this polymorphism on lung cancer. A meta-analysis of 15 studies with 4,932 lung cancer patients and 6,555...
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