Article
DNA repair in lung cancer: a large-scale quantitative analysis for polymorphisms in DNA repairing pathway genes and lung cancer susceptibility.
Expert review of respiratory medicine - 1 Sept 2022
Liao Zexi, Yi Minhan, Li Jiaxin, Zhang Yuan
Abstract excerpt
BACKGROUND: The results of associations between single nucleotide polymorphisms (SNPs) of genes in DNA repairing pathway and lung cancer (LC) risk are inconsistent. METHODS: We applied allele, dominant and recessive models to explore the risk of researched variants to LC in total LC and subgroups by ethnicity or LC subtypes with a cutoff point of p < 0.05. RESULTS: A total of 76,935 cases and 88,649 controls from...
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