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CellCelector™ as a platform in isolating primary B cells for antibody discovery

1 Jan 2022

Abstract excerpt

The most robust strategy in antibody discovery is the use of immunized animals and the ability to isolate and immortalize immune B-cells to hybridoma for further interrogation. However, capturing the full repertoire of an immunized animal is labor intensive, time consuming and limited in throughput. Therefore, techniques to directly mine the antibody repertoire of primary B-cells are of great importance in...

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PMID: 35059561
DOI: 10.1093/abt/tbab030

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