Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hybridoma technology: is it still useful?

1 Jan 2021

Abstract excerpt

The isolation of single monoclonal antibodies (mAbs) against a given antigen was only possible with the introduction of the hybridoma technology, which is based on the fusion of specific B lymphocytes with myeloma cells. Since then, several mAbs were described for therapeutic, diagnostic, and research purposes. Despite being an old technique with low complexity, hybridoma-based strategies have limitations that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35492397
DOI: 10.1016/j.crimmu.2021.03.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hybridoma technology: is it still useful?PMID 35492397Read ↗

Retrospective analysis of the preparation and application of immunotherapy in cancer treatment (Review)Semantic proximity Read ↗

Targeted fusion of Antibody-Secreting Cells: unlocking monoclonal antibody production with hybridoma technologySemantic proximity Read ↗

Functional Parameters of Hybridoma Cells: Methods of Evaluation and Biotechnological RelevanceSemantic proximity Read ↗

Engineering of monoclonal antibodies and antibody-based fusion proteins: successes and challenges.Semantic proximity Read ↗

Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage displaySemantic proximity Read ↗

Introduction to Antibody Engineering and Phage DisplaySemantic proximity Read ↗

In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery propertiesSemantic proximity Read ↗

Phage Display for the Generation of Antibodies for Proteome Research, Diagnostics and TherapySemantic proximity Read ↗

Generation of Murine Monoclonal Antibodies by Hybridoma TechnologySemantic proximity Read ↗

Generation of Murine Monoclonal Antibodies by Hybridoma TechnologySemantic proximity Read ↗

Phage display for discovery of anticancer antibodiesSemantic proximity Read ↗

Phage Display Derived Monoclonal Antibodies: From Bench to BedsideSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.