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NAb-seq: an accurate, rapid and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cells

2022-03-26

Abstract excerpt

<h4>ABSTRACT</h4> Despite their common use in research, monoclonal antibodies are currently not systematically sequenced. This can lead to issues with reproducibility and the occasional loss of antibodies with loss of cell lines. Hybridoma cell lines have been the primary means of generating monoclonal antibodies from immunized animals including mice, rats, rabbits and alpacas. Excluding therapeutic antibodies, f...

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Literature Corpus work
be665dcc-71f6-546b-b7bc-4dc0387dbff4
DOI
10.1101/2022.03.25.485728
Open publication

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NAb-seq: an accurate, rapid and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cellsDOI 10.1101/2022.03.25.485728
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