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Article

Effects of the Expression of Random Sequence Clones on Growth and Transcriptome Regulation in Escherichia coli.

Genes - 24 Dec 2021

Bhave Devika, Tautz Diethard

Abstract excerpt

Comparative genomic analyses have provided evidence that new genetic functions can emerge out of random nucleotide sequences. Here, we apply a direct experimental approach to study the effects of plasmids harboring random sequence inserts under the control of an inducible promoter. Based on data from previously described experiments dealing with the growth of clones within whole libraries, we extracted specific...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35052392
DOI: 10.3390/genes13010053
PMCID: PMC8775113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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