Article
JAK2 allele burden is correlated with a risk of venous but not arterial thrombosis.
Thrombosis research - 1 Mar 2022
Soudet Simon, Le Roy Gaelle, Cadet Estelle, Michaud Audrey, Morel Pierre, Marolleau Jean Pierre, Sevestre Marie Antoinette
Abstract excerpt
BACKGROUND: Thrombosis is the main complication in myeloproliferative neoplasms (MPN). A JAK2V617F mutation has been shown to be a risk factor for thrombosis. The implication of other risk factors alongside a mutation allele burden needs to be clarified (Trifa et al., 2018; Borowczyk et al., 2015). OBJECTIVE: Our aim was to investigate the role of the JAK2 mutation allele burden in the risk of cardiovascular...
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