Article
High prevalence of arterial thrombosis in JAK2 mutated essential thrombocythaemia: independence of the V617F allele burden.
Hematology (Amsterdam, Netherlands) - 1 Apr 2008
Larsen Thomas Stauffer, Pallisgaard Niels, Møller Michael Boe, Hasselbalch Hans Carl
Abstract excerpt
Approximately half of the patients with essential thrombocythaemia (ET) harbor the JAK2 V617F mutation. Despite a phenotypic mimicry of JAK2 V617F positive ET and polycythaemia vera (PV), the data on thromboembolic risk and correlation to JAK2 mutation status are ambiguous. On a strictly WHO defined ET cohort we evaluated possible clinical correlations to the JAK2 mutation status including a history of previous...
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