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Article

Clinical correlates of JAK2V617F allele burden in essential thrombocythemia.

Cancer - 1 Jun 2007

Kittur Jaya, Knudson Ryan A, Lasho Terra L, Finke Christy M, Gangat Naseema, Wolanskyj Alexandra P, Li Chin-Yang, Wu Wenting, Ketterling Rhett P, Pardanani Animesh, Tefferi Ayalew

Abstract excerpt

BACKGROUND: JAK2V617F occurs in approximately 50% of patients with essential thrombocythemia (ET). Qualitative studies of mutation analysis have previously reported an association between JAK2V617F and advanced age, higher hemoglobin level, higher leukocyte count, and lower platelet count. A possible association with thrombotic complication has also been considered. METHODS: Allele-specific, quantitative...

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Aged, 80 and over
Bone Marrow
DNA Mutational Analysis
DNA, Neoplasm
Janus Kinase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thrombocythemia, Essential

Venous Thrombosis

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PMID: 17440984
DOI: 10.1002/cncr.22663

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