Article
The JAK2 V617F mutational status and allele burden may be related with the risk of venous thromboembolic events in patients with Philadelphia-negative myeloproliferative neoplasms.
Thrombosis research - 1 Feb 2015
Borowczyk Martyna, Wojtaszewska Marzena, Lewandowski Krzysztof, Gil Lidia, Lewandowska Maria, Lehmann-Kopydłowska Agata, Kroll-Balcerzak Renata, Balcerzak Andrzej, Iwoła Małgorzata, Michalak Michał, Komarnicki Mieczysław
Abstract excerpt
INTRODUCTION: Patients with Philadelphia-negative myeloproliferative neoplasms (Ph(-) MPNs) are at increased risk of thromboembolic and hemorrhagic complications. The aim of the study was to determine the relationship between JAK2 V617F mutational status, JAK2 V617F allele burden and the risk of vascular complications occurrence. MATERIALS AND METHODS: Analysis was performed in a cohort of 186 patients diagnosed...
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