Article
Thromboses and hemorrhages are common in MPN patients with high JAK2V617F allele burden.
Annals of hematology - 1 Aug 2017
Bertozzi Irene, Bogoni Giulia, Biagetti Giacomo, Duner Elena, Lombardi Anna Maria, Fabris Fabrizio, Randi Maria Luigia
Abstract excerpt
The most common causes of morbidity and mortality in myeloproliferative neoplasms (MPN) are thrombotic and hemorrhagic complications. The JAK2V617F mutation, commonly found in MPN, correlates with several clinical and laboratory characteristics even if the relevance of JAK2V617F allele burden in the natural history of these diseases is unclear. In this study we searched, a relation between thrombotic and...
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