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Article

A review of Plks: Thinking outside the (polo) box

20 Jan 2022

Abstract excerpt

The polo-like kinase (Plk) family is comprised of five different members (Plk1-5), each with their own distinct functions. Plk family members participate in pivotal cell division processes as well as in non-mitotic roles. Importantly, Plk expression has been correlated with various disease states, including cancer. Multiples therapies, which primarily target Plk1, are currently being investigated alone or in...

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PMID: 35049091
DOI: 10.1002/mc.23388

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