Article
Association of IGHM polymorphisms with susceptibility to type 1 diabetes.
Immunologic research - 1 Jun 2022
Ferjeni Zouidi, Raouia Fakhfakh, Abida O, Penha-Gonçalves C, Masmoudi H
Abstract excerpt
Differentiation of B lymphocytes is accompanied by a regulated switch in the expression pattern and stability of surface and secretory immunoglobulins (Igs). Several lines of evidence show that autoimmune responses evolving in much autoimmune pathologies were associated with a high level of humoral Ig, but their pathogenic role remains elusive. The aim of this study was to test the hypothesis that variants at the...
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