Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between alleles, haplotypes, and amino acid variations in HLA class II genes and type 1 diabetes in Kuwaiti children.

Frontiers in immunology - 1 Jan 2023

Dashti Mohammed, Nizam Rasheeba, Jacob Sindhu, Al-Kandari Hessa, Al Ozairi Ebaa, Thanaraj Thangavel Alphonse, Al-Mulla Fahd

Abstract excerpt

Type 1 diabetes (T1D) is a complex autoimmune disorder that is highly prevalent globally. The interactions between genetic and environmental factors may trigger T1D in susceptible individuals. HLA genes play a significant role in T1D pathogenesis, and specific haplotypes are associated with an increased risk of developing the disease. Identifying risk haplotypes can greatly improve the genetic scoring for early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acids

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Genes, MHC Class II

Share to Haplotypes

Share to HLA-DRB1 Chains

Share to Kuwait

Source

Open in PubMed Open full text

Identifiers

PMID: 37638053
DOI: 10.3389/fimmu.2023.1238269
PMCID: PMC10457110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between alleles, haplotypes, and amino acid variations in HLA class II genes and type 1 diabetes in Kuwaiti children.PMID 37638053Read ↗

HLA class II alleles and haplotypes associated with susceptibility to type 1 diabetes and to type 1 diabetes with concomitant autoimmune diseases: a cross-sectional study from Eastern Croatia.Semantic proximity Read ↗

Association of protein tyrosine phosphatase non-receptor type 22 gene functional variant C1858T, HLA-DQ/DR genotypes and autoantibodies with susceptibility to type-1 diabetes mellitus in Kuwaiti Arabs.Semantic proximity Read ↗

Clinical features, epidemiology, autoantibody status, HLA haplotypes and genetic mechanisms of type 1 diabetes mellitus among children in Qatar.Semantic proximity Read ↗

Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries.Semantic proximity Read ↗

Clinical features, Epidemiology, Autoantibody status, HLA Haplotypes and Genetic Mechanisms of Type 1 diabetes mellitus among Children in QatarSemantic proximity Read ↗

The past, present, and future of genetic associations in type 1 diabetes.Semantic proximity Read ↗

Association of HLA-DR-DQ alleles, haplotypes, and diplotypes with type 1 diabetes in Saudis.Semantic proximity Read ↗

Immunogenetics of type 1 diabetes: A comprehensive review.Semantic proximity Read ↗

Deciphering the Genetic Landscape: Exploring the Relationship Between HLA-DQA1, HLA-DQB1, and HLA-DRB1 Genes in Diabetes MellitusSemantic proximity Read ↗

Genetic association and machine learning improves discovery and prediction of type 1 diabetesSemantic proximity Read ↗

Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions.Semantic proximity Read ↗

Complete HLA genotyping of type 1 diabetes patients and controls from Mali reveals both expected and novel disease associations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.