Article
Rifampin resistance mutations in the rpoB gene of Enterococcus faecalis impact host macrophage cytokine production.
Cytokine - 1 Mar 2022
Urusova Darya V, Merriman Joseph A, Gupta Ananya, Chen Liang, Mathema Barun, Caparon Michael G, Khader Shabaana A
Abstract excerpt
Antibiotic-resistant bacteria in the genus Enterococcus are a major cause of nosocomial infections and are an emergent public health concern. Similar to a number of bacterial species, resistance to the antibiotic rifampicin (RifR) in enterococci is associated with mutations in the gene encoding the β subunit of RNA polymerase (rpoB). In Mycobacterium tuberculosis, RifRrpoB mutations alter mycobacterial surface...
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