Article
Genetic diversity within leukemia-associated immunophenotype-defined subclones in AML.
Annals of hematology - 1 Mar 2022
Tiso F, Koorenhof-Scheele T N, Huys E, Martens J H A, de Graaf A O, van der Reijden B A, Langemeijer S M C, Preijers F W M B, Kroeze L I, Jansen J H
Abstract excerpt
Acute myeloid leukemia (AML) is a highly heterogeneous disease showing dynamic clonal evolution patterns over time. Various subclones may be present simultaneously and subclones may show a different expansion pattern and respond differently to applied therapies. It is already clear that immunophenotyping and genetic analyses may yield overlapping, but also complementary information. Detailed information on the...
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