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Article

Prevalence of pathogenic germline cancer risk variants in testicular cancer patients: Identifying high risk groups.

Urologic oncology - 1 Mar 2022

Ramamurthy Chethan, Nassar Amin H, Abou Alaiwi Sarah, Adib Elio, Akl Elie W, Yang Shan, Esplin Edward D, Liss Michael A, Tomlinson Gail E, Sonpavde Guru P

Abstract excerpt

BACKGROUND: Germline studies in testicular cancer have focused on unselected populations but so far have not led to recommendations for testicular cancer screening. OBJECTIVE: Herein, we hypothesized that men with testicular cancer and an additional risk factor for hereditary cancer predisposition carry a higher rate of pathogenic variants than men with testicular cancer without another risk factor. METHODS AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35022142
DOI: 10.1016/j.urolonc.2021.12.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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