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When Should Tumor Genomic Profiling Prompt Consideration of Germline Testing?

1 Sept 2019

Abstract excerpt

Somatic genomic testing is rapidly becoming an integral part of care for patients with metastatic cancer. Extrapolation of these results beyond personalized cancer therapy is a skill being demanded of practicing oncologists without prior specialty in genetics. Up to 12% of tumor genomic profiling reports will reveal a germline pathogenic variant. Recognition of these germline variants is essential not only for...

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PMID: 31509718
DOI: 10.1200/jop.19.00201

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