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The germline mutational landscape of genitourinary cancers and its indication for prognosis and risk

30 Nov 2022

Abstract excerpt

BACKGROUND: Germline mutations represent a high risk of hereditary cancers in population. The landscape and characteristics of germline mutations in genitourinary cancer are largely unknown, and their correlation with patient prognosis has not been defined. METHODS: Variant data and relevant clinical data of 10,389 cancer patients in The Cancer Genome Atlas (TCGA) database was downloaded. The subset of data of...

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PMID: 36451132
DOI: 10.1186/s12894-022-01141-1

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