Article

Germline testing data validate inferences of mutational status for variants detected from tumor-only sequencing

2021-04-15

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Background</h4> Pathogenic germline variants (PGV) in cancer susceptibility genes are usually identified in cancer patients through germline testing of DNA from blood or saliva: their detection can impact patient treatment options and potential risk reduction strategies for relatives. PGV can also be identified, in tumor sequencing assays, often performed without matched normal s...

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Literature Corpus work: 294e92fd-d7ff-5dc8-93ef-3186b7d410f9
DOI: 10.1101/2021.04.14.439855

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