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The Future of Parallel Tumor and Germline Genetic Testing: Is There a Role for All Patients With Cancer?

Journal of the National Comprehensive Cancer Network : JNCCN - 28 Jul 2021

Liu Ying L, Stadler Zsofia K

Abstract excerpt

Under the traditional paradigm of genetic testing in cancer, the role of germline testing was to assess for the inherited risk of cancer, whereas the role of tumor testing was to determine therapeutic selection. Parallel tumor-normal genetic testing uses simultaneous genetic testing of the tumor and normal tissue to identify mutations and allows their classification as either germline or somatic. The increasing...

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Identifiers

PMID: 34340209
DOI: 10.6004/jnccn.2021.7044
PMCID: PMC11123333

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