Article
Clinical significance of gene polymorphisms for hereditary predisposition to breast and ovarian cancer (review of literature).
Klinicheskaia laboratornaia diagnostika - 21 Dec 2021
Vodolazhsky D I, Mayakovskaya A V, Kubyshkin A V, Aliev K A, Fomochkina I I
Abstract excerpt
The review presents classical and modern views on the molecular genetic causes underlying hereditary predisposition to breast and ovarian cancer. A computerized literature search was carried out in the electronic databases MEDLINE, Scopus, and Web of Science, published between January 1994 and May 2021, using the keywords: «hereditary breast and ovarian cancer», «BRCA» and «DNA repair». Current views on the role...
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