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Article

Ovarian cancer predisposition beyond BRCA1 and BRCA2 genes.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Nov 2020

Pietragalla Antonella, Arcieri Martina, Marchetti Claudia, Scambia Giovanni, Fagotti Anna

Abstract excerpt

Several genes associated with hereditary ovarian cancer have been discovered as a result of the work done with next generation sequencing. It is estimated that approximately 23% of ovarian carcinomas have a hereditary predisposition. The most common hereditary condition is represented by germline mutations in BRCA1 or BRCA2 genes that account for 20-25% of high grade serous ovarian cancer. A number of other...

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Source

Identifiers

PMID: 32895312
DOI: 10.1136/ijgc-2020-001556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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