Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality.

Frontiers in immunology - 1 Jan 2021

Bartens Marie-Christine, Gibson Amanda J, Etherington Graham J, Di Palma Federica, Holder Angela, Werling Dirk, Willcocks Sam

Abstract excerpt

Recent evidence suggests that several cattle breeds may be more resistant to infection with the zoonotic pathogen Mycobacterium bovis. Our data presented here suggests that the response to mycobacterial antigens varies in macrophages generated from Brown Swiss (BS) and Holstein Friesian (HF) cattle, two breeds belonging to the Bos taurus family. Whole genome sequencing of the Brown Swiss genome identified several...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breeding
Share to Cattle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to Mycobacterium bovis

Share to Mycobacterium Infections

Share to Mycobacterium tuberculosis

Share to Polymorphism, Single Nucleotide

Share to Toll-Like Receptor 2

Source

Open in PubMed Open full text

Identifiers

PMID: 35003078
DOI: 10.3389/fimmu.2021.764390
PMCID: PMC8732954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality.PMID 35003078Read ↗

Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune FunctionalitySemantic proximity Read ↗

Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection.Semantic proximity Read ↗

Analysis of sequence variability and protein domain architectures for bovine peptidoglycan recognition protein 1 and Toll-like receptors 2 and 6.Semantic proximity Read ↗

Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattleSemantic proximity Read ↗

Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease.Semantic proximity Read ↗

Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle.Semantic proximity Read ↗

Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance.Semantic proximity Read ↗

Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle.Semantic proximity Read ↗

Determination of Genetic Variations of Toll-like Receptor (TLR) 2, 4 and 6 with Next Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein FriesianSemantic proximity Read ↗

Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis.Semantic proximity Read ↗

Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis).Semantic proximity Read ↗

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune ResponseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.