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Article

Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jan 2010

Seabury Christopher M, Seabury Paul M, Decker Jared E, Schnabel Robert D, Taylor Jeremy F, Womack James E

Abstract excerpt

The Toll-like receptor (TLR) and peptidoglycan recognition protein 1 (PGLYRP1) genes play key roles in the innate immune systems of mammals. While the TLRs recognize a variety of invading pathogens and induce innate immune responses, PGLYRP1 is directly microbicidal. We used custom allele-specific assays to genotype and validate 220 diallelic variants, including 54 nonsynonymous SNPs in 11 bovine innate immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 20018671
DOI: 10.1073/pnas.0913006107
PMCID: PMC2806759

Genes

PGLYRP1
TLR10
TLR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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