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Article

Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis).

BMC genetics - 14 Dec 2014

Alfano Flora, Peletto Simone, Lucibelli Maria Gabriella, Borriello Giorgia, Urciuolo Giovanna, Maniaci Maria Grazia, Desiato Rosanna, Tarantino Michela, Barone Amalia, Pasquali Paolo, Acutis Pier Luigi, Galiero Giorgio

Abstract excerpt

BACKGROUND: Toll-like receptors play a key role in innate immunity by recognizing pathogens and activating appropriate responses. Pathogens express several signal molecules (pathogen-associated molecular patterns, PAMPs) essential for survival and pathogenicity. Recognition of PAMPs triggers an array of anti-microbial immune responses through the induction of various inflammatory cytokines. The objective of this...

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Source

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Identifiers

PMID: 25496717
DOI: 10.1186/s12863-014-0139-y
PMCID: PMC4278265

Genes

TLR2
TLR4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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