Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle.

Journal of dairy science - 1 Jul 2011

Ruiz-Larrañaga O, Manzano C, Iriondo M, Garrido J M, Molina E, Vazquez P, Juste R A, Estonba A

Abstract excerpt

Toll-like receptors (TLR) are membrane proteins that play a key role in innate immunity, by recognizing pathogens and subsequently activating appropriate responses. Mutations in TLR genes are associated with susceptibility to inflammatory and infectious diseases in humans. In cattle, 3 members of the TLR family, TLR1, TLR2, and TLR4, are associated with Mycobacterium avium ssp. paratuberculosis infection,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cattle Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Mycobacterium avium subsp. paratuberculosis

Share to Paratuberculosis

Share to Toll-Like Receptor 1

Share to Toll-Like Receptor 2

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 21700053
DOI: 10.3168/jds.2010-3788

Genes

TLR4
TLR1
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle.PMID 21700053Read ↗

Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection.Semantic proximity Read ↗

Association of TLR4 polymorphisms with Mycobacterium avium subspecies paratuberculosis infection status in Canadian Holsteins.Semantic proximity Read ↗

Toll-like receptors TLR1, TLR2 and TLR4 gene mutations and natural resistance to Mycobacterium avium subsp. paratuberculosis infection in cattle.Semantic proximity Read ↗

Determination of Genetic Variations of Toll-like Receptor (TLR) 2, 4 and 6 with Next Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein FriesianSemantic proximity Read ↗

Polymorphisms in toll-like receptor (TLR) 1, 4, 9 and SLC11A1 genes and their association with paratuberculosis susceptibility in Holstein and indigenous crossbred cattle in TurkeySemantic proximity Read ↗

Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis.Semantic proximity Read ↗

Polymorphisms in toll-like receptor 1 and 9 genes and their association with tuberculosis susceptibility in Chinese Holstein cattle.Semantic proximity Read ↗

Candidate gene polymorphisms (BoIFNG, TLR4, SLC11A1) as risk factors for paratuberculosis infection in cattle.Semantic proximity Read ↗

Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis).Semantic proximity Read ↗

Prospects of toll-like receptors in dairy cattle breeding.Semantic proximity Read ↗

Functional polymorphisms in Toll-like receptor genes for innate immunity in farm animals.Semantic proximity Read ↗

Innate immune gene variation and differential susceptibility to uterine diseases in Holstein cows.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.