Association between single nucleotide polymorphism of rs1937 in TFAM gene and longevity among the elderly Chinese population: based on the CLHLS study.

doi:10.1186/s12877-021-02655-3

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Association between single nucleotide polymorphism of rs1937 in TFAM gene and longevity among the elderly Chinese population: based on the CLHLS study.

BMC geriatrics - 3 Jan 2022

Chen Qing, Li Zhi-Hao, Song Wei-Qi, Yao Yao, Zhang Yu-Jie, Zhong Wen-Fang, Zhang Pei-Dong, Liu Dan, Zhang Xi-Ru, Huang Qing-Mei, Zhao Xiao-Yang, Shi Xiao-Ming, Mao Chen

Abstract excerpt

BACKGROUND: To investigate whether the mitochondrial transcription factor A (TFAM) rs1937 single nucleotide polymorphism (SNP) is associated with longevity. METHODS: We conducted a case-control study among Chinese long-lived individuals (≥90 years). Data were obtained on 3294 participants who were able to voluntarily provided a saliva sample during 2008-2009 from the Chinese Longitudinal Healthy Longevity Survey...

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PMID: 34979947
DOI: 10.1186/s12877-021-02655-3
PMCID: PMC8722189

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