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Article

Telomerase Reverse Transcriptase Promoter Mutations in Human Hepatobiliary, Pancreatic and Gastrointestinal Cancer Cell Lines.

In vivo (Athens, Greece) - 1 Jan 2000

Hirata Masahiro, Fujita Koji, Fujihara Shintaro, Mizuo Takaaki, Nakabayashi Ryota, Kono Toshiaki, Namima Daisuke, Fujita Naoki, Yamana Hiroki, Kamada Hideki, Tani Joji, Kobara Hideki, Tsutsui Kunihiko, Matsuda Yoko, Ono Masafumi, Masaki Tsutomu

Abstract excerpt

BACKGROUND/AIM: The promoter region of the telomerase reverse transcriptase (TERT) gene is a regulatory element capable of affecting TERT expression, telomerase activity, and telomerase length. Mutations within the TERT promoter region are the most common mutations in many cancers. In this study, we characterized the TERT promoter mutation status in hepatobiliary, pancreatic, and gastrointestinal cancer cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34972704
DOI: 10.21873/invivo.12680
PMCID: PMC8765179

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