Article
A replication study separates polymorphisms behind migraine with and without depression.
PloS one - 1 Jan 2021
Petschner Peter, Baksa Daniel, Hullam Gabor, Torok Dora, Millinghoffer Andras, Deakin J F William, Bagdy Gyorgy, Juhasz Gabriella
Abstract excerpt
The largest migraine genome-wide association study identified 38 candidate loci. In this study we assessed whether these results replicate on a gene level in our European cohort and whether effects are altered by lifetime depression. We tested SNPs of the loci and their vicinity with or without interaction with depression in regression models. Advanced analysis methods such as Bayesian relevance analysis and a...
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