Article
Molecular genetic overlap between migraine and major depressive disorder.
European journal of human genetics : EJHG - 1 Aug 2018
Yang Yuanhao, Zhao Huiying, Boomsma Dorret I, Ligthart Lannie, Belin Andrea C, Smith George Davey, Esko Tonu, Freilinger Tobias M, Hansen Thomas Folkmann, Ikram M Arfan, Kallela Mikko, Kubisch Christian, Paraskevi Christofidou, Strachan David P, Wessman Maija, van den Maagdenberg Arn M J M, Terwindt Gisela M, Nyholt Dale R
Abstract excerpt
Migraine and major depressive disorder (MDD) are common brain disorders that frequently co-occur. Despite epidemiological evidence that migraine and MDD share a genetic basis, their overlap at the molecular genetic level has not been thoroughly investigated. Using single-nucleotide polymorphism (SNP) and gene-based analysis of genome-wide association study (GWAS) genotype data, we found significant genetic...
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