Article
Genome-wide association studies in non-anxiety individuals identified novel risk loci for depression.
European psychiatry : the journal of the Association of European Psychiatrists - 22 Jun 2022
Cheng Bolun, Qi Xin, Meng Peilin, Cheng Shiqiang, Yang Xuena, Liu Li, Yao Yao, Jia Yumeng, Wen Yan, Zhang Feng
Abstract excerpt
BACKGROUND: Depression is a debilitating mental disorder that often coexists with anxiety. The genetic mechanisms of depression and anxiety have considerable overlap, and studying depression in non-anxiety samples could help to discover novel gene. We assess the genetic variation of depression in non-anxiety samples, using genome-wide association studies (GWAS) and linkage disequilibrium score regression (LDSC)....
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