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Article

Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling study

1 Oct 2024

Abstract excerpt

Background In patients with colorectal cancer (CRC), the therapeutic effects of conventional immune checkpoint inhibitors targeting the adaptive immune system are largely limited to those with microsatellite instability-high tumors. Meanwhile, new immunotherapies targeting the innate immune system are attracting increasing attention. CD47 is a representative innate immune checkpoint involved in the evasion of...

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PMID: 39500526
DOI: 10.1136/jitc-2024-010326

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