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Article

Association Between Prekallikrein and Stroke: A Mendelian Randomization Study.

Journal of the American Heart Association - 15 Aug 2023

Wang Yinan, Jia Yiming, Xu Qingyun, Yang Pinni, Sun Lulu, Liu Yi, Chang Xinyue, He Yu, Shi Mengyao, Guo Daoxia, Zhang Yonghong, Zhu Zhengbao

Abstract excerpt

Background High plasma prekallikrein was reported to be associated with increased risks of stroke, but the causality for these associations remains unclear. We aimed to investigate the associations of genetically predicted plasma prekallikrein concentrations with all-cause stroke, ischemic stroke, 3 ischemic stroke subtypes, and intracerebral hemorrhage (ICH) using a 2-sample Mendelian randomization approach....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37581399
DOI: 10.1161/JAHA.123.030525
PMCID: PMC10492928

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