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Article

Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study.

Stroke - 1 Apr 2022

Frerich Simon, Malik Rainer, Georgakis Marios K, Sinner Moritz F, Kittner Steven J, Mitchell Braxton D, Dichgans Martin

Abstract excerpt

BACKGROUND: Observational studies suggest an association of stroke with cardiac traits beyond atrial fibrillation, the leading source of cardioembolism. However, controversy remains regarding a causal role of these traits in stroke pathogenesis. Here, we leveraged genetic data to systematically assess associations between cardiac traits and stroke risk using a Mendelian Randomization framework. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34911345
DOI: 10.1161/STROKEAHA.121.036306
PMCID: PMC10510836

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