Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolite Genome-Wide Association Study for Indoleamine 2,3-Dioxygenase Activity Associated with Chronic Kidney Disease.

Genes - 27 Nov 2021

Kim Hye-Rim, Jin Hyun-Seok, Eom Yong-Bin

Abstract excerpt

Chronic kidney disease (CKD) causes progressive damage to kidney function with increased inflammation. This process contributes to complex amino acid changes. Indoleamine 2,3-dioxygenase (IDO) has been proposed as a new biomarker of CKD in previous studies. In our research, we performed a metabolite genome-wide association study (mGWAS) to identify common and rare variants associated with IDO activity in a Korean...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers
Share to Creatinine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Glomerular Filtration Rate

Share to Indoleamine-Pyrrole 2,3,-Dioxygenase

Share to Metabolome

Share to Renal Insufficiency, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 34946851
DOI: 10.3390/genes12121905
PMCID: PMC8701662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolite Genome-Wide Association Study for Indoleamine 2,3-Dioxygenase Activity Associated with Chronic Kidney Disease.PMID 34946851Read ↗

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and diseaseSemantic proximity Read ↗

Integrated genomics and metabolomics in nephrologySemantic proximity Read ↗

Role of indoleamine 2,3-dioxygenase in health and diseaseSemantic proximity Read ↗

Emerging Roles of Xanthine Oxidoreductase in Chronic Kidney DiseaseSemantic proximity Read ↗

Identification and Validation of Tryptophan Metabolism–Related Genes in Diabetic Kidney Disease and Construction of a Clinical Prediction ModelSemantic proximity Read ↗

BHD-associated kidney cancer exhibits unique molecular characteristics and a wide variety of variants in chromatin remodeling genesSemantic proximity Read ↗

Indoleamine 2,3-Dioxygenase 2 (IDO2): The Protein That Lived TwiceSemantic proximity Read ↗

The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease ProgressionSemantic proximity Read ↗

Mendelian Randomization Identified SLC2A9 as a Novel cis-eQTL-Mediated Susceptibility Gene in Suppressing Renal Cancer and Its Related Metabolic Mechanisms.Semantic proximity Read ↗

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It ComplicatedSemantic proximity Read ↗

Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients.Semantic proximity Read ↗

Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.