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Integrated genomics and metabolomics in nephrology

22 Dec 2013

Abstract excerpt

Applying 'omics' approaches such as genome-wide association studies (GWAS) and metabolome analyses, genes and metabolites have been identified to be associated with renal pathophysiology. Meta-analyses of GWAS from large epidemiologic cohorts uncovered several novel loci linked with estimated glomerular filtration rate and chronic kidney disease (CKD). Sophisticated analytical technologies, including mass...

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PMID: 24366899
DOI: 10.1093/ndt/gft492

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