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Article

Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients.

Hereditas - 19 Jan 2022

Cao Tingming, Dai Guangming, Chu Hongqian, Kong Chengcheng, Duan Huijuan, Tian Na, Sun Zhaogang

Abstract excerpt

PURPOSE: To explore the role and effects of the single-nucleotide polymorphisms (SNPs) of the two functionally related indoleamine 2,3-dioxygenase (IDO) isoforms on IDO activity in the Chinese Han ethnic population. METHODS: A total of 151 consecutive patients of Chinese Han ethnicity (99 men and 52 women; average age 51.92 ± 18.26 years) with pulmonary TB admitted to Beijing Chest Hospital between July 2016 and...

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Identifiers

PMID: 35045867
DOI: 10.1186/s41065-022-00219-y
PMCID: PMC8767668

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