Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biological and Clinical Implications of TNF-α Promoter and CYP1B1 Gene Variations in Coronary Artery Disease Susceptibility.

Cardiovascular & hematological disorders drug targets - 1 Jan 2021

Mir Rashid, Elfaki Imadeldin, Jha Chandan K, Javid Jamsheed, Babakr Abdullatif T, Banu Shaheena, Mir Mohammad M, Jamwal Dheeraj, Khullar Naina, Alzahrani Khalid J, Chahal Sukh M S

Abstract excerpt

BACKGROUND: Cardiovascular diseases (CVD) are important causes of death worldwide. Atherosclerosis is a chronic inflammatory disorder. It is the major cause of CVD and is manifested by ischemic heart disease or coronary artery disease (CAD). TNF-α is a pro-inflammatory cytokine that regulates immune response and promotes the development of atherosclerosis. Cytochrome p450 1B1 (CYP1B1) is an enzyme involved in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1B1

Share to Genetic Predisposition to Disease

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 34939556
DOI: 10.2174/1871529X22666211221151830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biological and Clinical Implications of TNF-α Promoter and CYP1B1 Gene Variations in Coronary Artery Disease Susceptibility.PMID 34939556Read ↗

Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian.Semantic proximity Read ↗

Association of tumor necrosis factor-α gene polymorphisms and coronary artery disease susceptibility: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of tumor necrosis factor-α -308 G/A gene polymorphism with coronary artery diseases: An evidence-based study.Semantic proximity Read ↗

TNF-α polymorphisms and coronary artery disease: association study in the Korean population.Semantic proximity Read ↗

Polymorphisms of the tumour necrosis factor‐α gene, coronary heart disease and obesitySemantic proximity Read ↗

TNFR2 gene polymorphism in coronary artery disease.Semantic proximity Read ↗

Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population.Semantic proximity Read ↗

TNF-alpha-308G>A polymorphism and the risk of familial CAD in a Pakistani population.Semantic proximity Read ↗

Association of TNF-α promoter gene G-308A polymorphism with metabolic syndrome, insulin resistance, serum TNF-α and leptin levels in Indian adult women.Semantic proximity Read ↗

Tumor necrosis factor receptor 2 gene (TNFRSF1B) in genetic basis of coronary artery disease.Semantic proximity Read ↗

Association of the -1031T>C polymorphism and soluble TNF-α levels with Acute Coronary Syndrome.Semantic proximity Read ↗

There is no association between TNF-α gene polymorphisms and the risk of coronary artery heart disease: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.