Article
Tumor necrosis factor receptor 2 gene (TNFRSF1B) in genetic basis of coronary artery disease.
Journal of molecular medicine (Berlin, Germany) - 1 Apr 2001
Benjafield A V, Wang X L, Morris B J
Abstract excerpt
Tumor necrosis factor (TNF)-alpha has been implicated in pathophysiological processes in coronary artery disease (CAD). TNF receptor 2 is of particular interest in mediating such effects. The gene for this receptor (TNF-RSF1B) has, moreover, been implicated in hypertension, elevated cholesterol and insulin resistance. TNFRSF1B is thus a worthy candidate in studies of the genetic basis of CAD. We therefore...
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