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Article

Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population.

Gene - 10 Sept 2017

Mastana Sarabjit, Prakash Swayam, Akam Elizabeth C, Kirby Melissa, Lindley Martin R, Sinha Nakul, Agrawal Suraksha

Abstract excerpt

BACKGROUND: Cytokines regulate the expression of inflammatory molecules which destabilize the atheromatic plaques. This study focuses on studying the association of inflammatory cytokine polymorphisms like TNF-α -308 (G/A), TNF-β +252 (A/G), IL-6 -174 (G/C) and IL-6 -597 (G/A), and IFN-ɣ +874 (T/A) with coronary artery disease (CAD) among north Indian patients. MATERIALS AND METHODS: 143 CAD and 137 normal...

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Source

Identifiers

PMID: 28739396
DOI: 10.1016/j.gene.2017.07.050

Genes

TNF
CAD
APOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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